The game was less then three minutes old when Kaden Jones sliced through the line and ran 35 yards for a touchdown to give Chandler a 7-0 lead against Prague.
It was a lead the Lions never relinquished, and the play became a blueprint for the game.
The Lions went on to run for 318 yards and ran for eight touchdowns.
Casmen Hill led the way with 150 yards and four scores on 15 carries. Carson Clagg added two touchdowns and Drake Rodriguez added another.
Despite the lop-sided score and the offensive stats, Chandler coach Jack Gray wasn’t ready to throw roses.
“Prague had a lot of guys injured,” he said. “There are a lot of things we have to work on.
“I wasn’t satisfied at all. We have to get better and fine-tune a lot of stuff.”
The Lions finished at 7-3, playing in what appears the stacked district in the state. Prague, for example, finished fifth and was two games over .500.
The seven teams in the district were 18-5 outside the league.
Chandler hosts Alva Friday in the first round of the playoffs, while Prague will head to Blackwell to face the 5-4 Maroons.
Prague and Blackwell have one common opponent: Luther.
Prague beat the Lions 27-14 in the season opener at Luther, while Luther put a 49-7 woodshedding on Blackwell.
Despite its injuries, Prague showed its explosiveness against Chandler, getting a 68-yard first-half touchdown run from quarterback Trip Davis, who appeared trapped near the goal line but juked into the end zone.
He came back in the second half for a touchdown run that was 43 yards as the ref walks but covered maybe 110 yards total.
He started to the left, reversed his course, curled back to the right and sprinted to the end zone.
Defensively for Chandler, Carson Clagg and Dalton Fowble had seven tackles each.
Rodriguez, Stefaun Mackey, Kyle Snodgrass and Johin Marshall had five each.